Jakarta, February 26, 2025 – In an effort oppose cancer the lungs are getting bigger increase prevalence , technology Next-Generation Sequencing (NGS) is here as solution innovative For more personalized and precise treatment target . Round-table discussion organized by KALGen Innolab discuss how NGS can revolutionize treatment cancer lungs through inspection more molecular efficient and accurate .

What is Next-Generation Sequencing (NGS)?

NGS is technology sophisticated that allows inspection many genes at once in One time . This method No only save time , but also save sample , so that allow treatment precision For cancer lungs . According to Dr. Sita Laksmi Andarini , Ph.D , SpP (K), a specialist lung , cancer lungs own Lots oncogenic driver or change genetics that cause tumors. With NGS, mutations specific to cancer lungs can identified , allowing more targeted therapy effective .

Types of Lung Cancer and Their Importance Diagnosis Molecular

Cancer lungs consists of of two types Main : Small Cell Lung Cancer (SCLC) and Non-Small Cell Lung Cancer (NSCLC). NSCLC is the most common type , with subtype like adenocarcinoma , squamous cell carcinoma , and large cell carcinoma . Diagnosis cancer lungs now No only depend on pathology anatomy , but also involves diagnosis molecular . EGFR mutations , in particular exon 19 deletion and exon 21 L858R mutation , often found in adenocarcinoma lungs .

The Role of EGFR Mutations in Treatment Lung Cancer

According to consent Assidicky , Laboratory Manager KALGen Innolab , EGFR mutations are mutation the most common genetic found in cancer lungs , with number incidence of 10-30% in NSCLC. Some targeted drugs such as gefitinib, erlotinib, afatinib, and osimertinib has proven effective for NSCLC with EGFR mutations . In addition , the drug new like amivantamab is also being developed For handle resistant EGFR mutations to anti-EGFR therapy .

The advantages of NGS in Treatment Lung Cancer

NGS allows identification acquired resistance to targeted therapy , so that help doctor in choose proper treatment . KALGen Innolab has adopting the Illumina NextSeq-2000 OncoGS platform for inspection cancer lungs , which allows testing up to 60 samples in one batch. This platform also expands gene coverage to 15 genes, increasing flexibility in cancer profiling .

Importance External Quality Assurance (PME)

Ahmad, Consultant Biomolecular , emphasizing the importance of PME as proof guarantee quality laboratory . As first partnership laboratory between Indonesia and Japan , KALGen Innolab committed For provide service inspection cancer fast , accurate and responsive lungs .

KALGen Academia: A Place for Collaboration and Education

KALGen Academia is designed for experts , doctors , researchers and practitioners laboratory medical For collaborate and develop self through various activity education scientific . With with the theme " Towards World Class Medical Laboratory ", KALGen Academia aims increase quality service health in the field laboratory medical .

For information more further , contact the KALGen Hotline Innolab .

Quick Q&A:

Q: What is Next-Generation Sequencing (NGS)?     
 A: NGS is technology that enables inspection many genes at once in One time , help identification mutation genetics in cancer lungs For more treatment precision .

Q: Why? diagnosis molecular important in cancer lungs ?          
 A: Diagnosis molecular help identify mutation genetics such as EGFR which affects choice treatment , so that therapy can more personal and effective .

Q: What are they? type cancer most common lung cancer ?       
A: Cancer lungs consists of of two types Main : Small Cell Lung Cancer (SCLC) and Non-Small Cell Lung Cancer (NSCLC). NSCLC is the most common , with subtype like adenocarcinoma .

Q: What is the role EGFR mutations in treatment cancer lungs ?           
 A: EGFR mutations are change genetics that often found in cancer lungs . Targeted drugs such as gefitinib and osimertinib effective for NSCLC with EGFR mutation .

Q: How does NGS help? in treatment cancer lungs ?         
A: NGS helps identify mutation genetic and acquired resistance to targeted therapy , allowing doctor choose proper treatment .

Q: What are the advantages of the Illumina NextSeq-2000            
OncoGS platform ? A: This platform allow testing up to 60 samples in one batch and expand gene coverage to 15 genes, increasing efficiency and accuracy diagnosis .

Q: What is the purpose? KALGen Academia?          
 A: KALGen Academia aims to For increase quality service health through collaboration and education for experts , doctors and practitioners laboratory medical .

(Keyword: Laboratorium, Pemeriksaan, Kanker, Paru, panel, Multigen, Actionable, Pengobatan Presisi, Personalized Medicine, Precision Medicine)